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Version: 17.06d (Release date: 2017-06-26)
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Doxazosin Mesylate (Code C29005)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Doxazosin Mesylate

Definition: The mesylate salt form of doxazosin, a quinazoline compound with smooth muscle relaxing activity. Doxazosin mesylate selectively antagonizes alpha-1-adrenergic receptors in smooth muscle of the bladder neck and prostate, thereby relaxing the smooth muscle and decreasing the obstruction and urethral resistance seen with benign prostate hyperplasia (BPH). This may improve BPH symptoms. This agent also blocks alpha-1-adrenergic receptors in peripheral vascular smooth muscle, which leads to vasodilatation and a subsequent decrease in peripheral vascular resistance.

NCI-GLOSS Definition: A drug used to treat high blood pressure and urinary problems caused by an enlarged prostate. It relaxes muscle tissue in blood vessels and in the prostate. Cardura is a type of alpha blocker.

Label: Doxazosin Mesylate

NCI Thesaurus Code: C29005 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0077770  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Cardura
doxazosin
Doxazosin Mesylate
DOXAZOSIN MESYLATE
doxazosin mesylate

External Source Codes: 
CAS Registry Number 77883-43-3 (see NLM ChemIDplus info)
FDA UNII Code 86P6PQK0MU
ChEBI ID CHEBI:4709 (see ChEBI info)
UMLS CUI C0077770

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C23H25N5O5.CH4O3S
code C29005
Contributing_Source FDA
Legacy_Concept_Name Doxazosin_Mesylate
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C29005

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