|Doxazosin Mesylate (Code C29005)|
|Terms & Properties|
Preferred Name: Doxazosin Mesylate
Definition: The mesylate salt form of doxazosin, a quinazoline compound with smooth muscle relaxing activity. Doxazosin mesylate selectively antagonizes alpha-1-adrenergic receptors in smooth muscle of the bladder neck and prostate, thereby relaxing the smooth muscle and decreasing the obstruction and urethral resistance seen with benign prostate hyperplasia (BPH). This may improve BPH symptoms. This agent also blocks alpha-1-adrenergic receptors in peripheral vascular smooth muscle, which leads to vasodilatation and a subsequent decrease in peripheral vascular resistance.
NCI-GLOSS Definition: A drug used to treat high blood pressure and urinary problems caused by an enlarged prostate. It relaxes muscle tissue in blood vessels and in the prostate. Cardura is a type of alpha blocker.
Label: Doxazosin Mesylate
NCI Metathesaurus Link: C0077770 (see NCI Metathesaurus info)
Synonyms & Abbreviations: (see Synonym Details)
External Source Codes:
|CAS Registry Number||77883-43-3 (see NLM ChemIDplus info)|
|FDA UNII Code||86P6PQK0MU|
|ChEBI ID||CHEBI:4709 (see ChEBI info)|
|Name||Value (qualifiers indented underneath)|
Additional Concept Data:
|Defined Fully by Roles: No|