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Version: 17.06d (Release date: 2017-06-26)
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Citalopram Hydrobromide (Code C28932)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Citalopram Hydrobromide

Definition: The orally bioavailable hydrobromide salt of the racemic bicyclic phthalene derivative citalopram with antidepressant activity. As a selective serotonin reuptake inhibitor (SSRI), citalopram selectively inhibits the CNS neuronal reuptake of serotonin, thereby potentiating serotonergic activity in the central nervous system (CNS). This agent has minimal effects on the CNS neuronal reuptake of norepinephrine (NE) and dopamine (DA).

NCI-GLOSS Definition: A drug used to treat depression. It belongs to the families of drugs called antidepressant agents and selective serotonin reuptake inhibitors (SSRIs).

Display Name: Citalopram Hydrobromide

Label: Citalopram Hydrobromide

NCI Thesaurus Code: C28932 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0724555  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile Monohydrobromide
Celexa
citalopram
Citalopram Hydrobromide
CITALOPRAM HYDROBROMIDE
Elopram
Lu 10-171-B
Seropram

External Source Codes: 
CAS Registry Number 59729-32-7 (see NLM ChemIDplus info)
FDA UNII Code I1E9D14F36
ChEBI ID CHEBI:3724 (see ChEBI info)
PDQ Closed Trial Search ID 500063
PDQ Open Trial Search ID 500063 (check for NCI PDQ open clinical trial info)
UMLS CUI C0724555

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C20H21FN2O.BrH
code C28932
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Citalopram_Hydrobromide
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C28932

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