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Version: 17.06d (Release date: 2017-06-26)
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Aspirin (Code C287)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Aspirin

Definition: An orally administered non-steroidal antiinflammatory agent. Acetylsalicylic acid binds to and acetylates serine residues in cyclooxygenases, resulting in decreased synthesis of prostaglandin, platelet aggregation, and inflammation. This agent exhibits analgesic, antipyretic, and anticoagulant properties.

NCI-GLOSS Definition: A drug that reduces pain, fever, inflammation, and blood clotting. Aspirin belongs to the family of drugs called nonsteroidal anti-inflammatory agents. It is also being studied in cancer prevention.

Display Name: Aspirin

Label: Aspirin

NCI Thesaurus Code: C287 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0004057  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
2-(Acetyloxy)benzoic Acid
Acetylsalicylic Acid
Acetylsalicylic acid
ASA
Aspergum
Aspirin
ASPIRIN
aspirin
Ecotrin
Empirin
Entericin
Extren
Measurin

External Source Codes: 
CAS Registry Number 50-78-2 (see NLM ChemIDplus info)
FDA UNII Code R16CO5Y76E
ChEBI ID CHEBI:15365 (see ChEBI info)
NSC Code 406186 (see NCI DTP info)
PDQ Closed Trial Search ID 39152
PDQ Open Trial Search ID 39152 (check for NCI PDQ open clinical trial info)
UMLS CUI C0004057

Other Properties:
     Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Mild to moderate pain; fever; prevention of arterial and venous thrombosis
Chemical_Formula C9H8O4
code C287
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Acetylsalicylic_Acid
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C287

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