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Version: 16.10e (Release date: 2016-10-31)
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Therapeutic Tumor Infiltrating Lymphocytes (Code C28699)

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Terms & Properties

Preferred Name: Therapeutic Tumor Infiltrating Lymphocytes

Definition: A preparation of cells, consisting of autologous tumor infiltrating lymphocytes, that are manipulated in vitro and, upon administration in vivo, re-infiltrate the tumor to initiate tumor cell lysis. In vitro, therapeutic tumor-infiltrating lymphocytes (TILs) are isolated from tumor tissue and cultured with lymphokines such as interleukin-2; the therapeutic TILs are then infused into the patient, where, after re-infiltration of the tumor, they may induce lysis of tumor cells and tumor regression. The use of therapeutic TILs is considered a form of adoptive immunotherapy.

Display Name: Therapeutic Tumor Infiltrating Lymphocytes

Label: Therapeutic Tumor Infiltrating Lymphocytes

NCI Thesaurus Code: C28699 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1515408  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Therapeutic Tumor Infiltrating Lymphocytes
Tumor Infiltrating Lymphocytes

External Source Codes: 
PDQ Closed Trial Search ID 41004
PDQ Open Trial Search ID 41004 (check for NCI PDQ open clinical trial info)
UMLS CUI C1515408

Other Properties:
Name Value (qualifiers indented underneath)
code C28699
Contributing_Source CTRP
Legacy_Concept_Name Therapeutic_Tumor_Infiltrating_Lymphocytes
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C28699

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