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Version: 16.11d (Release date: 2016-11-28)
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Agatolimod Sodium (Code C28580)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Agatolimod Sodium

Definition: The tricosasodium salt of a synthetic 24-mer oligonucleotide containing 3 CpG motifs with potential antineoplastic and immunostimulatory activity. Agatolimod selectively targets Toll-like receptor 9 (TLR9), thereby activating dendritic and B cells and stimulating cytotoxic T cell and antibody responses against tumor cells bearing tumor antigens.

NCI-GLOSS Definition: A substance that is being studied in the treatment of some types of cancer. It belongs to the family of drugs called biological response modifiers.

Display Name: Agatolimod Sodium

Label: Agatolimod Sodium

NCI Thesaurus Code: C28580 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1436331  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
(3'-5')d(P-thio)(T-C-G-T-C-G-T-T-T-T-G-T-C-G-T-T-T-T-G-T-C-G-T-T) Tricosasodium Salt
Agatolimod Sodium
CpG 7909
PF-3512676
ProMune

External Source Codes: 
CAS Registry Number 541547-35-7 (see NLM ChemIDplus info)
NSC Code 731581 (see NCI DTP info)
PDQ Closed Trial Search ID 38660
PDQ Open Trial Search ID 38660 (check for NCI PDQ open clinical trial info)
UMLS CUI C1436331

Other Properties:
Name Value (qualifiers indented underneath)
code C28580
Contributing_Source CTRP
Legacy_Concept_Name CpG_7909
Semantic_Type Nucleic Acid, Nucleoside, or Nucleotide
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C28580

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