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Version: 17.06d (Release date: 2017-06-26)
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Recombinant Adenovirus-hIFN-beta (Code C28550)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Recombinant Adenovirus-hIFN-beta

Definition: A recombinant replication-defective adenovirus which encodes the gene for the cytokine human interferon-beta (IFN-beta). Once inserted into and replicating in host tumor cells, recombinant adenovirus-hIFN-beta expresses human IFN-beta, which may stimulate an antiproliferative natural killer (NK) cell response against tumor cells and induce caspase-mediated tumor cell apoptosis. (NCI04)

NCI-GLOSS Definition: A gene therapy agent that is being studied in the treatment of cancer. It belongs to the family of drugs called biological response modifiers.

Label: Recombinant Adenovirus-hIFN-beta

NCI Thesaurus Code: C28550 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1527241  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Ad-hIFN-beta
BG00001
Recombinant Adenovirus-hIFN-beta

External Source Codes: 
PDQ Closed Trial Search ID 38609
PDQ Open Trial Search ID 38609 (check for NCI PDQ open clinical trial info)
UMLS CUI C1527241

Other Properties:
     Name Value (qualifiers indented underneath)
code C28550
Legacy_Concept_Name Recombinant_Adenovirus-hIFN-beta
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C28550

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