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Version: 17.06d (Release date: 2017-06-26)
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Bismuth Bi213 Monoclonal Antibody M195 (Code C28502)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Bismuth Bi213 Monoclonal Antibody M195

Definition: A radioimmunoconjugate consisting of murine monoclonal antibody (M195) and bismuth 213 (Bi213). Monoclonal antibody M195 binds to CD33, a surface antigen expressed by myelogenous leukemia cells. Bismuth 213 is an isotope that emits short-ranged high-energy alpha particles. This radioimmunoconjugate selectively delivers alpha particle-mediated cytotoxicity to leukemic cells, thereby limiting the exposure of normal tissues to ionizing radiation. (NCI04)

Label: Bismuth Bi213 Monoclonal Antibody M195

NCI Thesaurus Code: C28502 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0935824  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Bismuth Bi213 Monoclonal Antibody M195

External Source Codes: 
PDQ Closed Trial Search ID 38271
PDQ Open Trial Search ID 38271 (check for NCI PDQ open clinical trial info)
UMLS CUI C0935824

Other Properties:
     Name Value (qualifiers indented underneath)
code C28502
Legacy_Concept_Name Bismuth_Bi213_Monoclonal_Antibody_M195
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C28502

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