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Version: 17.06d (Release date: 2017-06-26)
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MART-1:26-35(27L) Peptide Vaccine (Code C2772)

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Terms & Properties

Preferred Name: MART-1:26-35(27L) Peptide Vaccine

Definition: A peptide-based cancer vaccine consisting of amino acid residues 26 through 35 of MART-1 (melanoma antigen recognized by T-cells-1) with a leucine substitution at amino acid position 27 to improve immunogenicity. Upon administration, MART-1:26-35(27L) peptide vaccine may induce a cytotoxic T-lymphocyte (CTL) response against MART-1-expressing tumor cells, resulting in decreased tumor growth. The tumor-associated antigen (TAA) MART-1 may be overexpressed on melanoma cancer cells.

Display Name: MART-1:26-35(27L) Peptide Vaccine

Label: MART-1:26-35(27L) Peptide Vaccine

NCI Thesaurus Code: C2772 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1518107  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
MART-1:26-35(27L) Peptide Vaccine
MART-1:26-35 (27L)

External Source Codes: 
NSC Code 709401 (see NCI DTP info)
PDQ Closed Trial Search ID 599670
PDQ Open Trial Search ID 599670 (check for NCI PDQ open clinical trial info)
UMLS CUI C1518107

Other Properties:
     Name Value (qualifiers indented underneath)
code C2772
Contributing_Source CTRP
Legacy_Concept_Name MART-1_26-35_27L
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2772

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