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Version: 17.08d (Release date: 2017-08-28)
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Epoetin Alfa (Code C2695)

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Terms & Properties

Preferred Name: Epoetin Alfa

Definition: A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine human erythropoietin (EPO). Produced primarily by cells of the peritubular capillary endothelium of the kidney in response to hypoxia, circulating EPO binds to EPO receptors on the surface of committed erythroid progenitors in the bone marrow resulting in their replication and maturation into functional erythrocytes.

NCI-GLOSS Definition: A substance that is made in the laboratory and stimulates the bone marrow to make red blood cells. It is a type of antianemic and a type of recombinant human erythropoietin.

Display Name: Epoetin Alfa

Label: Epoetin Alfa

NCI Thesaurus Code: C2695 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0357126  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
EPO
Epoetin Alfa
epoetin alfa
Epogen
Eprex
Procrit

External Source Codes: 
CAS Registry Number 113427-24-0 (see NLM ChemIDplus info)
PDQ Closed Trial Search ID 41102
PDQ Open Trial Search ID 41102 (check for NCI PDQ open clinical trial info)
UMLS CUI C0357126

Other Properties:
     Name Value (qualifiers indented underneath)
code C2695
Contributing_Source CTRP
Legacy_Concept_Name Epoetin_Alfa
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2695

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