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National Cancer Institute
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Version: 17.06d (Release date: 2017-06-26)
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Recombinant Vaccinia-TRICOM Vaccine (Code C2685)

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Terms & Properties

Preferred Name: Recombinant Vaccinia-TRICOM Vaccine

Definition: A vaccine consisting of recombinant vaccinia virus encoding a TRIad of COstimulatory Molecules (B7-1, ICAM-1, and LFA-3; also called TRICOM). Vaccination with recombinant vaccinia-TRICOM vaccine stimulates the host immune system to mount a non-specific T-cell response. With the addition of a tumor-associated antigen peptide, this vaccine may enhance a tumor-specific immune response.

NCI-GLOSS Definition: A cancer vaccine made with a form of a vaccinia virus that does not cause disease in humans. It is being studied in the treatment of some types of cancer. The virus is changed in the laboratory to make human proteins that may help immune cells in the body kill tumor cells.

Display Name: Recombinant Vaccinia-TRICOM Vaccine

Label: Recombinant Vaccinia-TRICOM Vaccine

NCI Thesaurus Code: C2685 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1099097  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Recombinant Vaccinia-TRICOM Vaccine
recombinant vaccinia-TRICOM vaccine
vaccinia-TRICOM vaccine

External Source Codes: 
NSC Code 708039 (see NCI DTP info)
PDQ Closed Trial Search ID 38659
PDQ Open Trial Search ID 38659 (check for NCI PDQ open clinical trial info)
UMLS CUI C1099097

Other Properties:
     Name Value (qualifiers indented underneath)
code C2685
Contributing_Source CTRP
Legacy_Concept_Name Vaccinia-TRICOM_Vaccine
Semantic_Type Pharmacologic Substance
Semantic_Type Virus

Additional Concept Data: 
Defined Fully by Roles: No  


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