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Version: 17.06d (Release date: 2017-06-26)
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Talaporfin Sodium (Code C26675)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Talaporfin Sodium

Definition: An agent consisting of chlorin e6, derived from chlorophyll, and L-aspartic acid with photosensitizing activity. After intratumoral activation by light emitting diodes, taporfin sodium forms an extended high energy conformational state that generates singlet oxygen, resulting in free radical-mediated cell death. (NCI04)

NCI-GLOSS Definition: A drug used in photodynamic therapy. When absorbed by cancer cells and exposed to light, the drug becomes active and kills the cancer cells.

Display Name: Talaporfin Sodium

Label: Talaporfin Sodium

NCI Thesaurus Code: C26675 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C2350202  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Laserphyrin
LS11
ME2906
Mono-L-aspartyl Chlorin e6
NPe6
Talaporfin Sodium
TALAPORFIN SODIUM
talaporfin sodium
Taporfin Sodium

External Source Codes: 
CAS Registry Number 220201-34-3 (see NLM ChemIDplus info)
FDA UNII Code L63605PZ70
PDQ Closed Trial Search ID 258313
PDQ Open Trial Search ID 258313 (check for NCI PDQ open clinical trial info)
UMLS CUI C2350202

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C38H37N5O9.4Na
code C26675
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Taporfin_Sodium
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C26675

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