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Version: 17.02d (Release date: 2016-02-27)
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Soblidotin (Code C26672)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Soblidotin

Definition: A dolastatin-10 derivative. Soblidotin inhibits tubulin polymerization, resulting in cell cycle arrest and induction of apoptosis. (NCI04)

NCI-GLOSS Definition: A substance being studied in the treatment of cancer. It is a type of tubulin inhibitor.

Label: Soblidotin

NCI Thesaurus Code: C26672 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1328702  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Auristatin PE
N(2)-(N,N-Dimethyl-valyl)-N-(2-methoxy-4-(2-(1-methoxy-2-methyl-3-oxo-3-((2-phenylethyl)amino)propyl)-1-pyrrolidinyl)-1-(1-methylpropyl)-4-oxobutyl)-N-methyl-valinamide
SOBLIDOTIN
Soblidotin
soblidotin
TZT-1027

External Source Codes: 
CAS Registry Number 149606-27-9 (see NLM ChemIDplus info)
FDA UNII Code DQC51A0WQH
PDQ Closed Trial Search ID 302644
PDQ Open Trial Search ID 302644 (check for NCI PDQ open clinical trial info)
UMLS CUI C1328702

Other Properties:
Name Value (qualifiers indented underneath)
Chemical_Formula C39H67N5O6
code C26672
Contributing_Source FDA
Legacy_Concept_Name Soblidotin
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C26672

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