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Version: 17.06d (Release date: 2017-06-26)
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Recombinant Fowlpox-TRICOM Vaccine (Code C2667)

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Terms & Properties

Preferred Name: Recombinant Fowlpox-TRICOM Vaccine

Definition: A vaccine comprised of a recombinant fowlpox virus vector encoding a TRIad of COstimulatory Molecules (B7-1, ICAM-1 and LFA-3) (TRICOM), which may enhance antigen presentation and activate cytotoxic T-cells. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it is replication incompetent in mammalian cells. (NCI04)

NCI-GLOSS Definition: A cancer vaccine made with a form of a chicken virus that does not cause disease in humans. It is being studied in the treatment of some types of cancer. The virus is changed in the laboratory to make human proteins that may help immune cells in the body kill tumor cells.

Display Name: Recombinant Fowlpox-TRICOM Vaccine

Label: Recombinant Fowlpox-TRICOM Vaccine

NCI Thesaurus Code: C2667 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1134570  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Recombinant Fowlpox-TRICOM
Recombinant Fowlpox-TRICOM Vaccine
recombinant fowlpox-TRICOM vaccine
rF-TRICOM (B7.1.iCAM1-LFA3-Fowlpox)

External Source Codes: 
NSC Code 710658 (see NCI DTP info)
PDQ Closed Trial Search ID 38543
PDQ Open Trial Search ID 38543 (check for NCI PDQ open clinical trial info)
UMLS CUI C1134570

Other Properties:
     Name Value (qualifiers indented underneath)
code C2667
Contributing_Source CTRP
Legacy_Concept_Name Fowlpox-TRICOM_Vaccine
Semantic_Type Pharmacologic Substance
Semantic_Type Virus

Additional Concept Data: 
Defined Fully by Roles: No  


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