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Version: 17.06d (Release date: 2017-06-26)
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Modafinil (Code C26661)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Modafinil

Definition: A synthetic central nervous system stimulant with wakefulness-promoting activity. Modafinil appears to inhibit dopamine reuptake, resulting in an increase in extracellular dopamine. This agent exhibits pronounced wakefulness-promoting activity (without sympathomimetic activity) and may improve cognitive function in certain clinical settings. (NCI04)

NCI-GLOSS Definition: A drug that is being studied as a treatment for fatigue in patients with cancer. It belongs to the family of drugs called stimulants.

Display Name: Modafinil

Label: Modafinil

NCI Thesaurus Code: C26661 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0066677  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Modafinil
MODAFINIL
modafinil
Provigil

External Source Codes: 
CAS Registry Number 68693-11-8 (see NLM ChemIDplus info)
FDA UNII Code R3UK8X3U3D
PDQ Closed Trial Search ID 256449
PDQ Open Trial Search ID 256449 (check for NCI PDQ open clinical trial info)
UMLS CUI C0066677

Other Properties:
     Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Narcolepsy
Chemical_Formula C15H15NO2S
code C26661
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Modafinil
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C26661

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