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Version: 17.06d (Release date: 2017-06-26)
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Modafinil (Code C26661)

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Terms & Properties

Preferred Name: Modafinil

Definition: A synthetic central nervous system stimulant with wakefulness-promoting activity. Modafinil appears to inhibit dopamine reuptake, resulting in an increase in extracellular dopamine. This agent exhibits pronounced wakefulness-promoting activity (without sympathomimetic activity) and may improve cognitive function in certain clinical settings. (NCI04)

NCI-GLOSS Definition: A drug that is being studied as a treatment for fatigue in patients with cancer. It belongs to the family of drugs called stimulants.

Display Name: Modafinil

Label: Modafinil

NCI Thesaurus Code: C26661 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0066677  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)

External Source Codes: 
CAS Registry Number 68693-11-8 (see NLM ChemIDplus info)
PDQ Closed Trial Search ID 256449
PDQ Open Trial Search ID 256449 (check for NCI PDQ open clinical trial info)
UMLS CUI C0066677

Other Properties:
     Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Narcolepsy
Chemical_Formula C15H15NO2S
code C26661
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Modafinil
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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