|Hexaminolevulinate (Code C26654)|
|Terms & Properties|
Preferred Name: Hexaminolevulinate
Definition: The hexyl ester of 5-aminolevulinic acid (ALA) with photodynamic properties. As a precursor of photoactive porphorins, hexyl 5-aminolevulinate induces the endogenous production of the photosensitizer protoporphyrin IX (PPIX) which accumulates selectively in tumor tissue. When exposed to specific wavelengths of light, PPIX is activated and, depending on the wavelength and/or intensity of light, either fluoresces, thereby allowing tumor imaging, or induces tumor cell apoptosis.
NCI-GLOSS Definition: A substance that is used to find and kill tumor cells. It enters tumor cells and becomes activated when exposed to a special type of light. A chemical reaction causes the cells to produce fluorescent light and die.
Display Name: Hexaminolevulinate
NCI Metathesaurus Link: C1327841 (see NCI Metathesaurus info)
Synonyms & Abbreviations: (see Synonym Details)
External Source Codes:
|CAS Registry Number||140898-97-1 (see NLM ChemIDplus info)|
|FDA UNII Code||G7H20TKI67|
|PDQ Closed Trial Search ID||269130|
|PDQ Open Trial Search ID||269130 (check for NCI PDQ open clinical trial info)|
|Name||Value (qualifiers indented underneath)|
Additional Concept Data:
|Defined Fully by Roles: No|