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Version: 17.06d (Release date: 2017-06-26)
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Essiac (Code C26649)

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Terms & Properties

Preferred Name: Essiac

Definition: An herbal formula containing burdock root (Arctium lappa), Turkey rhubarb root (Rheum palmatum), sheep sorrel (Rumex acetosella), and slippery elm bark (Ulmus fulva) with potential immunostimulating, anti-inflammatory and anti-tumor activities. The extract's chemical profile, their respective concentrations and the mechanism of action of Essiac are largely unknown due to the proprietary nature of the formula and product inconsistency. Several chemical classes in Essiac are consistently represented and may attribute to its therapeutic effect, including anthraquinone derivatives such as rhein and emodin, high molecular polysaccharides, and lignans such as arctigenin. However, all these chemicals are unlikely to occur in high concentrations in Essiac, and its potential therapeutic effect may be attributed to a potential synergistic effect of these various compounds.

NCI-GLOSS Definition: An herbal tea mixture that contains burdock root, Indian rhubarb root, sheep sorrel, and slippery elm bark. It has been claimed to remove toxins from the body, make the immune system stronger, relieve pain, control diabetes, treat AIDS, reduce tumor size, increase cancer survival, and improve quality of life. No clinical trial using Essiac in humans has been reported in a peer-reviewed, scientific journal, and the FDA has not approved the use of Essiac for the treatment of any medical conditions.

Label: Essiac

NCI Thesaurus Code: C26649 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0673827  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)

External Source Codes: 
PDQ Closed Trial Search ID 304440
PDQ Open Trial Search ID 304440 (check for NCI PDQ open clinical trial info)
UMLS CUI C0673827

Other Properties:
     Name Value (qualifiers indented underneath)
code C26649
Legacy_Concept_Name Essiac
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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