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Version: 17.12d (Release date: 2017-12-26)
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Black Cohosh (Code C26647)

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Terms & Properties

Preferred Name: Black Cohosh

Definition: A triterpene-containing herb isolated from the roots and rhizomes of the plant Cimicifuga racemosa (also known as Actaea racemosa). While the mechanism of action of black cohosh is not completely understood, it appears to act as a selective estrogen receptor modulator. In vitro, this preparation has been shown to induce cell cycle arrest and caspase-dependent apoptosis of estrogen-sensitive breast cancer cells. (NCI04)

NCI-GLOSS Definition: An eastern North American perennial herb. A substance obtained from the root of the plant has been used in some cultures to treat a number of medical problems. It is being studied in the treatment of hot flashes and other symptoms of menopause. The scientific name is Cimicifuga racemosa.

Label: Black Cohosh

NCI Thesaurus Code: C26647 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0771967  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Actaea racemosa Root
Black Cohosh
black cohosh
black snakeroot
Cimicifuga racemosa Root
Cimicifugae racemosae Rhizoma
Fariy Candle Root
rattlesnake root

External Source Codes: 
FDA UNII Code K73E24S6X9
PDQ Closed Trial Search ID 302635
PDQ Open Trial Search ID 302635 (check for NCI PDQ open clinical trial info)
UMLS CUI C0771967

Other Properties:
     Name Value (qualifiers indented underneath)
code C26647
Contributing_Source FDA
Legacy_Concept_Name Black_Cohosh
Semantic_Type Plant

Additional Concept Data: 
Defined Fully by Roles: No  


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