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National Cancer Institute
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Version: 17.10e (Release date: 2017-10-30)
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OSE 2101 (Code C26645)

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Terms & Properties

Preferred Name: OSE 2101

Definition: A proprietary cancer DNA vaccine that contains multiple natural and modified epitopes derived from the four tumor associated antigens, CEA, HER2/neu, p53, and MAGE 2/3. EP-2101 also includes CAP1-6D, a heteroclitic CEA analog, and PADRE, a proprietary universal T-cell epitope that serves to enhance the immunogenicity of the epitopes. This agent has been shown to elicit cytotoxic T-lymphocyte responses against tumor cells expressing these multiple epitopes. (NCI04)

NCI-GLOSS Definition: A substance that is being studied as a treatment for cancer. It belongs to the family of drugs called cancer vaccines.

Label: OSE 2101

NCI Thesaurus Code: C26645 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C2606659  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
OSE 2101

External Source Codes: 
PDQ Closed Trial Search ID 301640
PDQ Open Trial Search ID 301640 (check for NCI PDQ open clinical trial info)
UMLS CUI C2606659

Other Properties:
     Name Value (qualifiers indented underneath)
code C26645
Legacy_Concept_Name EP-2101
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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