|Epoetin Beta (Code C26639)|
|Terms & Properties|
Preferred Name: Epoetin Beta
Definition: A recombinant therapeutic agent that is chemically identical to or similar to the endogenous cytokine human erythropoietin (EPO). Produced primarily by cells of the peritubular capillary endothelium of the kidney in response to hypoxia, circulating EPO binds to EPO receptors on the surface of committed erythroid progenitors in the bone marrow resulting in their replication and maturation into functional erythrocytes.
NCI-GLOSS Definition: A substance that is made in the laboratory and stimulates the bone marrow to make red blood cells. It is a type of antianemic and a type of recombinant human erythropoietin.
Label: Epoetin Beta
NCI Metathesaurus Link: C0376540 (see NCI Metathesaurus info)
Synonyms & Abbreviations: (see Synonym Details)
External Source Codes:
|PDQ Closed Trial Search ID||257861|
|PDQ Open Trial Search ID||257861 (check for NCI PDQ open clinical trial info)|
|Name||Value (qualifiers indented underneath)|
|Accepted_Therapeutic_Use_For||Anemia associated with end-stage renal disease|
|Semantic_Type||Amino Acid, Peptide, or Protein|
Additional Concept Data:
|Defined Fully by Roles: No|