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Version: 17.06d (Release date: 2017-06-26)
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Dendritic Cell-Autologous Lung Tumor Vaccine (Code C26446)

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Terms & Properties

Preferred Name: Dendritic Cell-Autologous Lung Tumor Vaccine

Definition: A cancer vaccine consisting of lymphocytes harvested from a patient with lung cancer and induced to become antigen-presenting cells (APCs) known as dendritic cells. The dendritic cells are transduced with the gene encoding an antigen specific to the patient's cancer and then returned to the patient. In the host, the altered cells stimulate the immune system to mount a primary T cell response against lung tumor cells expressing the target antigen. Dendritic cell-autologous lung tumor vaccines have been investigated for use in cancer immunotherapy. (NCI04)

Label: Dendritic Cell-Autologous Lung Tumor Vaccine

NCI Thesaurus Code: C26446 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1327750  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
DCVax-Lung
Dendritic Cell-Autologous Lung Tumor Vaccine

External Source Codes: 
PDQ Closed Trial Search ID 256453
PDQ Open Trial Search ID 256453 (check for NCI PDQ open clinical trial info)
UMLS CUI C1327750

Other Properties:
     Name Value (qualifiers indented underneath)
code C26446
Legacy_Concept_Name Dendritic_Cell-Autologous_Lung_Tumor_Vaccine
Semantic_Type Immunologic Factor
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C26446

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