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National Cancer Institute
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Version: 17.06d (Release date: 2017-06-26)
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Autologous Dendritic Cell-Adenovirus P53 Vaccine (Code C26445)

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Terms & Properties

Preferred Name: Autologous Dendritic Cell-Adenovirus P53 Vaccine

Definition: An autologous vaccine composed of dendritic cells (DC) that have been transduced with a p53 tumor suppressor gene-modified virus. When the autologous dendritic cell-adenovirus p53 vaccine is administered, the host cytotoxic T lymphocytes (CTL) are directed against p53-positive tumor cells, which may result in tumor cell death and decreased tumor growth. (NCI04)

Display Name: Autologous Dendritic Cell-Adenovirus P53 Vaccine

Label: Autologous Dendritic Cell-Adenovirus P53 Vaccine

NCI Thesaurus Code: C26445 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1327799  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Autologous Dendritic Cell-Adenovirus P53 Vaccine

External Source Codes: 
PDQ Closed Trial Search ID 258292
PDQ Open Trial Search ID 258292 (check for NCI PDQ open clinical trial info)
UMLS CUI C1327799

Other Properties:
     Name Value (qualifiers indented underneath)
code C26445
Contributing_Source CTRP
Legacy_Concept_Name Autologous_Dendritic_Cell-Adenovirus_P53_Vaccine
Semantic_Type Immunologic Factor
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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