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National Cancer Institute
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Version: 17.12d (Release date: 2017-12-26)
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I 131 Monoclonal Antibody CC49 (Code C26442)

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Terms & Properties

Preferred Name: I 131 Monoclonal Antibody CC49

Definition: A radioimmunoconjugate of the humanized monoclonal antibody CC49 labeled with iodine I 131. Iodine I 131 monoclonal antibody CC49 delivers beta and gamma radiation-emitting I 131 radionuclide specifically to tumor cells that express tumor-associated glycoprotein (TAG)-72, allowing localization of TAG-72-expressing tumor cells with radioimaging devices in diagnostic applications or resulting in specific TAG-72-expressing tumor cell radiocytotoxicity in therapeutic applications. Monoclonal antibody CC49 binds to TAG-72, a pancarcinoma antigen, with high affinity.

Label: I 131 Monoclonal Antibody CC49

NCI Thesaurus Code: C26442 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1327845  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
I 131 Monoclonal Antibody CC49
Iodine I 131 Monoclonal Antibody CC49

External Source Codes: 
PDQ Closed Trial Search ID 269166
PDQ Open Trial Search ID 269166 (check for NCI PDQ open clinical trial info)
UMLS CUI C1327845

Other Properties:
     Name Value (qualifiers indented underneath)
code C26442
Legacy_Concept_Name I_131_Monoclonal_Antibody_CC49
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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