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National Cancer Institute
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Version: 17.06d (Release date: 2017-06-26)
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Iratumumab (Code C26441)

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Terms & Properties

Preferred Name: Iratumumab

Definition: A fully human monoclonal antibody with potential antineoplastic activity. MDX-060 is a fully humanized antibody that targets CD30, a member of the tumor necrosis factor receptor superfamily found on activated lymphocytes. CD30 is over-expressed in various lymphoproliferative disorders, Hodgkin's disease and other lymphomas, and other cancers. (NCI04)

NCI-GLOSS Definition: A monoclonal antibody that is being studied in the treatment of some lymphomas. Monoclonal antibodies are produced in the laboratory and can locate and bind to cancer cells.

Display Name: Iratumumab

Label: Iratumumab

NCI Thesaurus Code: C26441 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1327954  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Monoclonal Antibody MDX-060

External Source Codes: 
CAS Registry Number 640735-09-7 (see NLM ChemIDplus info)
PDQ Closed Trial Search ID 301900
PDQ Open Trial Search ID 301900 (check for NCI PDQ open clinical trial info)
UMLS CUI C1327954

Other Properties:
     Name Value (qualifiers indented underneath)
code C26441
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name MDX-060_Monoclonal_Antibody
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Indicator, Reagent, or Diagnostic Aid

Additional Concept Data: 
Defined Fully by Roles: No  


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