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Version: 17.06d (Release date: 2017-06-26)
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Iratumumab (Code C26441)

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Terms & Properties

Preferred Name: Iratumumab

Definition: A fully human monoclonal antibody with potential antineoplastic activity. MDX-060 is a fully humanized antibody that targets CD30, a member of the tumor necrosis factor receptor superfamily found on activated lymphocytes. CD30 is over-expressed in various lymphoproliferative disorders, Hodgkin's disease and other lymphomas, and other cancers. (NCI04)

NCI-GLOSS Definition: A monoclonal antibody that is being studied in the treatment of some lymphomas. Monoclonal antibodies are produced in the laboratory and can locate and bind to cancer cells.

Display Name: Iratumumab

Label: Iratumumab

NCI Thesaurus Code: C26441 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1327954  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Iratumumab
IRATUMUMAB
MDX-060
Monoclonal Antibody MDX-060

External Source Codes: 
CAS Registry Number 640735-09-7 (see NLM ChemIDplus info)
FDA UNII Code AYH22O1B1U
PDQ Closed Trial Search ID 301900
PDQ Open Trial Search ID 301900 (check for NCI PDQ open clinical trial info)
UMLS CUI C1327954

Other Properties:
     Name Value (qualifiers indented underneath)
code C26441
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name MDX-060_Monoclonal_Antibody
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Indicator, Reagent, or Diagnostic Aid

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C26441

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