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National Cancer Institute
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Version: 17.06d (Release date: 2017-06-26)
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GPI-0100 (Code C2627)

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Terms & Properties

Preferred Name: GPI-0100

Definition: A semi-synthetic triterpene glycoside, derived from the naturally occurring saponins. GPI-0100 functions as an adjuvant when given as part of a vaccine preparation to improve the immunogenicity of antigens such as proteins, carbohydrates. GPI-0100 containing vaccines have been used with both viral and tumor antigens to elicit a Type 1 helper T cell response for those diseases in which a cytotoxic T lymphocyte (CTL) response is desired.

Label: GPI-0100

NCI Thesaurus Code: C2627 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0935831  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)

External Source Codes: 
PDQ Closed Trial Search ID 38278
PDQ Open Trial Search ID 38278 (check for NCI PDQ open clinical trial info)
UMLS CUI C0935831

Other Properties:
     Name Value (qualifiers indented underneath)
code C2627
Legacy_Concept_Name GPI-0100
Semantic_Type Immunologic Factor
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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