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Version: 17.06d (Release date: 2017-06-26)
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Recombinant Vaccinia-CEA(6D)-TRICOM Vaccine (Code C2619)

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Terms & Properties

Preferred Name: Recombinant Vaccinia-CEA(6D)-TRICOM Vaccine

Definition: A vaccine consisting of recombinant vaccinia virus encoding the tumor-associated antigen carcinoembryonic antigen (CEA) and a TRIad of COstimulatory Molecules (B7-1, ICAM-1, and LFA-3; also called TRICOM). Vaccination with recombinant vaccinia-CEA(6D)-TRICOM vaccine stimulates the host immune system to mount a T-cell response against tumor cells expressing the CEA antigen. The use of TRICOM in the vaccine may elicit a greater antitumor cytotoxic T lymphocyte (CTL) immune response compared to the use of vaccinia-CEA alone.

Display Name: Recombinant Vaccinia-CEA(6D)-TRICOM Vaccine

Label: Recombinant Vaccinia-CEA(6D)-TRICOM Vaccine

NCI Thesaurus Code: C2619 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0935789  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Recombinant Vaccinia-CEA(6D)-TRICOM Vaccine
rV-CEA(6D)-TRICOM
Vaccinia-CEA-TRICOM Vaccine

External Source Codes: 
NSC Code 710067 (see NCI DTP info)
PDQ Closed Trial Search ID 38215
PDQ Open Trial Search ID 38215 (check for NCI PDQ open clinical trial info)
UMLS CUI C0935789

Other Properties:
     Name Value (qualifiers indented underneath)
code C2619
Contributing_Source CTRP
Legacy_Concept_Name Vaccinia-CEA-TRICOM_Vaccine
Semantic_Type Pharmacologic Substance
Semantic_Type Virus

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2619

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