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Version: 17.06d (Release date: 2017-06-26)
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Yttrium Y-90 Epratuzumab Tetraxetan (Code C2582)

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Terms & Properties

Preferred Name: Yttrium Y-90 Epratuzumab Tetraxetan

Definition: A radioimmunotherapeutic humanized murine monoclonal antibody (LL2) directed against the CD22 pan-B-cell antigen and chelated to the radioisotope yttrium-90 (Y 90). Y 90 humanized monoclonal antibody LL2 binds to tumor cells expressing CD22, delivering a cytotoxic dose of beta radiation.

Display Name: Yttrium Y-90 Epratuzumab Tetraxetan

Label: Yttrium Y-90 Epratuzumab Tetraxetan

NCI Thesaurus Code: C2582 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0879352  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Monoclonal antibody LL2, yttrium Y 90
Y90 Humanized Epratuzumab Tetraxetan
Yttrium Y-90 Epratuzumab Tetraxetan
YTTRIUM Y-90 EPRATUZUMAB TETRAXETAN
Yttrium Y 90 Humanized Epratuzumab Tetraxetan
Yttrium Y 90 Humanized Monoclonal Antibody LL2
yttrium Y 90 MOAB LL2
Y 90 Humanized Monoclonal Antibody LL2
Y 90 MoAb LL2
Y 90 monoclonal antibody LL2

External Source Codes: 
CAS Registry Number 501423-25-2 (see NLM ChemIDplus info)
FDA UNII Code J36232195E
PDQ Closed Trial Search ID 43648
PDQ Open Trial Search ID 43648 (check for NCI PDQ open clinical trial info)
UMLS CUI C0879352

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C16H25N5O7.Y
code C2582
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Y_90_Humanized_Monoclonal_Antibody_LL2
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2582

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