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Version: 17.06d (Release date: 2017-06-26)
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Liothyronine Sodium (Code C2581)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Liothyronine Sodium

Definition: The sodium salt form of liothyronine, a synthetic form of the levorotatory isomer of the naturally occurring thyroid hormone triiodothyronine (T3). Liothyronine sodium binds to nuclear thyroid receptors which then bind to thyroid hormone response elements of target genes. As a result, liothyronine sodium induces gene expression that is required for normal growth and development. Liothyronine sodium is more potent and has a more rapid action than thyroxine (T4).

NCI-GLOSS Definition: A drug that is used to treat certain thyroid (a gland located near the voice box) conditions. It is also being studied in the treatment of thyroid cancer. Cytomel is made in the laboratory and is a form of the thyroid hormone triiodthyronine (T3).

Display Name: Liothyronine Sodium

Label: Liothyronine Sodium

NCI Thesaurus Code: C2581 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0546882  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Cytomel
Liothyronine Sodium
liothyronine sodium
LIOTHYRONINE SODIUM
Triostat

External Source Codes: 
CAS Registry Number 55-06-1 (see NLM ChemIDplus info)
FDA UNII Code GCA9VV7D2N
ChEBI ID CHEBI:6484 (see ChEBI info)
PDQ Closed Trial Search ID 43629
PDQ Open Trial Search ID 43629 (check for NCI PDQ open clinical trial info)
UMLS CUI C0546882

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C15H11I3NO4.Na
code C2581
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Liothyronine_Sodium
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2581

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