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National Cancer Institute
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Version: 17.06d (Release date: 2017-06-26)
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Interleukin-2 Gene (Code C2549)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Interleukin-2 Gene

Definition: The DNA sequence that encodes the protein cytokine interleukin-2 (IL-2). When introduced as the complementary DNA (cDNA) form into tumor cells by, for example, a genetically engineered adenovirus vector, the transfected IL-2 cDNA expresses IL-2 which may activate antitumoral natural killer cells and elicit an antitumoral cytotoxic T-cell response, resulting in an inhibition of tumor progression. (NCI04)

Display Name: Interleukin-2 Gene

Label: Interleukin-2 Gene

NCI Thesaurus Code: C2549 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL448417  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
IL-2 Gene
Interleukin-2 Gene

External Source Codes: 
PDQ Closed Trial Search ID 38045
PDQ Open Trial Search ID 38045 (check for NCI PDQ open clinical trial info)

Other Properties:
     Name Value (qualifiers indented underneath)
code C2549
Contributing_Source CTRP
Legacy_Concept_Name Interleukin-2_Gene
Semantic_Type Gene or Genome
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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