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Version: 17.06d (Release date: 2017-06-26)
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Autologous Expanded Mesenchymal Stem Cells OTI-010 (Code C2534)

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Terms & Properties

Preferred Name: Autologous Expanded Mesenchymal Stem Cells OTI-010

Definition: Multipotent self-renewing adherent non-hematopoietic stromal cells harvested from a patient's bone marrow and grown in vitro. When injected back into the patient, autologous expanded mesenchymal stem cells OTI-010 may differentiate into various mesenchyme-derived cell types and, in some instances, may augment bone marrow engraftment after whole-body irradiation.

NCI-GLOSS Definition: A product that is made of special stem cells taken from a patient's bone marrow and grown in the laboratory. After a patient's bone marrow is destroyed by treatment with whole body irradiation or chemotherapy, these cells are injected back into the patient to help rebuild bone marrow. Stromagen has been studied in the prevention of graft-versus-host disease during stem cell transplant in patients receiving treatment for cancer. Stromagen is used in cellular therapy.

Label: Autologous Expanded Mesenchymal Stem Cells OTI-010

NCI Thesaurus Code: C2534 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1510983  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
autologous expanded mesenchymal stem cells OTI-010
Autologous Expanded Mesenchymal Stem Cells OTI-010
OTI-010
Stromagen

External Source Codes: 
PDQ Closed Trial Search ID 361537
PDQ Open Trial Search ID 361537 (check for NCI PDQ open clinical trial info)
UMLS CUI C1510983

Other Properties:
     Name Value (qualifiers indented underneath)
code C2534
Legacy_Concept_Name Autologous_Expanded_Mesenchymal_Stem_Cells
Semantic_Type Cell
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2534

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