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Version: 17.06d (Release date: 2017-06-26)
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Vaccinia-Tyrosinase Vaccine (Code C2531)

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Terms & Properties

Preferred Name: Vaccinia-Tyrosinase Vaccine

Definition: A vaccine consisting of recombinant vaccinia virus, based on the modified vaccinia virus Ankara (MVA) that encodes the melanoma-associated antigen tyrosinase. Vaccination with vaccinia-tyrosinase may stimulate the host immune system to mount a cytotoxic T-cell response against tumor cells expressing tyrosinase. Tyrosinase is a melanoma-specific differentiation agent that catalyzes the synthesis of the melanin precursor L-3,4-dihydroxyphenylalanine (L-DOPA).

Label: Vaccinia-Tyrosinase Vaccine

NCI Thesaurus Code: C2531 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0796657  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Recombinant Vaccinia-Tyrosinase
Recombinant Vaccinia-Tyrosinase Vaccine
rV-TYR Vaccine
Vaccinia-Tyrosinase Vaccine

External Source Codes: 
NSC Code 702140 (see NCI DTP info)
PDQ Closed Trial Search ID 43488
PDQ Open Trial Search ID 43488 (check for NCI PDQ open clinical trial info)
UMLS CUI C0796657

Other Properties:
     Name Value (qualifiers indented underneath)
code C2531
Legacy_Concept_Name Vaccinia-Tyrosinase_Vaccine
Semantic_Type Immunologic Factor
Semantic_Type Pharmacologic Substance
Semantic_Type Virus

Additional Concept Data: 
Defined Fully by Roles: No  


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