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National Cancer Institute
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Version: 17.12d (Release date: 2017-12-26)
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GVAX Prostate Cancer Vaccine (Code C2525)

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Terms & Properties

Preferred Name: GVAX Prostate Cancer Vaccine

Definition: A whole cell vaccine expressing human granulocyte macrophage-colony stimulating factor (GM-CSF) with potential antineoplastic activity. Tumor cells from prostate cancer patients are harvested and then genetically modified to secrete GM-CSF, an immune stimulatory growth factor that plays a key role in stimulating the body's immune responses against tumor cells. Because the vaccine is derived from allogenic cells, it has demonstrated a favorable side effect profile than other approaches of delivering long-lasting GM-CSF.

Display Name: GVAX Prostate Cancer Vaccine

Label: GVAX Prostate Cancer Vaccine

NCI Thesaurus Code: C2525 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0796615  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Allogeneic Prostate Cancer Vaccine, GM- CSF Gene Transduced
Allogenic Prostate GVAX
GM-CSF Gene Transduced Allogeneic Prostate Cancer Vaccine
GM-CSF prostate cancer vaccine
GVAX Allogeneic Prostate Cancer Vaccine
GVAX Allogenic Prostate Cancer Vaccine
GVAX Prostate
GVAX Prostate Cancer Vaccine
Prostate Cancer Vaccine, GM-CSF Gene Transduced
Prostate Cancer Vaccine, GVAX

External Source Codes: 
PDQ Closed Trial Search ID 43459
PDQ Open Trial Search ID 43459 (check for NCI PDQ open clinical trial info)
UMLS CUI C0796615

Other Properties:
     Name Value (qualifiers indented underneath)
code C2525
Contributing_Source CTRP
Legacy_Concept_Name GVAX_Prostate_Cancer_Vaccine
Semantic_Type Immunologic Factor
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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