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National Cancer Institute
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Version: 17.08d (Release date: 2017-08-28)
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AFP Gene Hepatocellular Carcinoma Vaccine (Code C2512)

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Terms & Properties

Preferred Name: AFP Gene Hepatocellular Carcinoma Vaccine

Definition: A cancer vaccine composed of naked plasmid DNA of the gene for the tumor-associated antigen alpha-fetoprotein (AFP), a macromolecule that acts as a specific immunologic target for hepatocellular carcinoma. This agent exerts an antitumor effect by inducing cytotoxic T-lymphocytes to attack AFP-expressing tumor cells. (NCI04)

Label: AFP Gene Hepatocellular Carcinoma Vaccine

NCI Thesaurus Code: C2512 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0796510  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
AFP Gene Hepatocellular Carcinoma Vaccine
vaccine, AFP gene hepatocellular carcinoma

External Source Codes: 
PDQ Closed Trial Search ID 43366
PDQ Open Trial Search ID 43366 (check for NCI PDQ open clinical trial info)
UMLS CUI C0796510

Other Properties:
     Name Value (qualifiers indented underneath)
code C2512
Legacy_Concept_Name AFP_Gene_Hepatocellular_Carcinoma_Vaccine
Semantic_Type Immunologic Factor
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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