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National Cancer Institute
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Version: 17.06d (Release date: 2017-06-26)
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PSA Prostate Cancer Vaccine (Code C2497)

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Terms & Properties

Preferred Name: PSA Prostate Cancer Vaccine

Definition: A peptide vaccine containing the prostate specific antigen (PSA) with potential antineoplastic activity. PSA, a glycoprotein secreted by prostatic epithelial and ductal cells, is overexpressed in prostate cancer cells and is used as a tumor marker for both diagnosis and treatment evaluation. Vaccination with PSA peptide vaccine may produce anti-PSA antibodies as well as elicit a cytotoxic T-cell (CTL) response against prostate cancer cells expressing this antigen, thereby decreasing tumor cell growth.

Display Name: PSA Prostate Cancer Vaccine

Label: PSA Prostate Cancer Vaccine

NCI Thesaurus Code: C2497 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0919275  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
PSA Prostate Cancer Vaccine

External Source Codes: 
PDQ Closed Trial Search ID 43250
PDQ Open Trial Search ID 43250 (check for NCI PDQ open clinical trial info)
UMLS CUI C0919275

Other Properties:
     Name Value (qualifiers indented underneath)
code C2497
Contributing_Source CTRP
Legacy_Concept_Name PSA_Prostate_Cancer_Vaccine
Semantic_Type Immunologic Factor
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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