|13-Deoxydoxorubicin (Code C2494)|
|Terms & Properties|
Preferred Name: 13-Deoxydoxorubicin
Definition: An analogue of the anthracycline antineoplastic antibiotic doxorubicin. 13-Deoxydoxorubicin intercalates DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent was designed to be a non-cardiotoxic anthracycline antibiotic.
NCI-GLOSS Definition: An anticancer drug that belongs to the family of drugs called antitumor antibiotics. It is an anthracycline.
NCI Metathesaurus Link: C0796383 (see NCI Metathesaurus info)
Synonyms & Abbreviations: (see Synonym Details)
External Source Codes:
|PDQ Closed Trial Search ID||43222|
|PDQ Open Trial Search ID||43222 (check for NCI PDQ open clinical trial info)|
|Name||Value (qualifiers indented underneath)|
Additional Concept Data:
|Defined Fully by Roles: No|