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National Cancer Institute
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Version: 17.10e (Release date: 2017-10-30)
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13-Deoxydoxorubicin (Code C2494)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: 13-Deoxydoxorubicin

Definition: An analogue of the anthracycline antineoplastic antibiotic doxorubicin. 13-Deoxydoxorubicin intercalates DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent was designed to be a non-cardiotoxic anthracycline antibiotic.

NCI-GLOSS Definition: An anticancer drug that belongs to the family of drugs called antitumor antibiotics. It is an anthracycline.

Label: 13-Deoxydoxorubicin

NCI Thesaurus Code: C2494 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0796383  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)

External Source Codes: 
PDQ Closed Trial Search ID 43222
PDQ Open Trial Search ID 43222 (check for NCI PDQ open clinical trial info)
UMLS CUI C0796383

Other Properties:
     Name Value (qualifiers indented underneath)
code C2494
Legacy_Concept_Name GPX-100
Semantic_Type Antibiotic
Semantic_Type Organic Chemical

Additional Concept Data: 
Defined Fully by Roles: No  


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