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Version: 17.06d (Release date: 2017-06-26)
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Iodine I 131 Monoclonal Antibody 81C6 (Code C2488)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Iodine I 131 Monoclonal Antibody 81C6

Definition: A radioimmunoconjugate consisting of 81C6, a murine IgG2 anti-tenascin monoclonal antibody labeled with iodine 131 (I-131), with radioimaging and radioimmunotherapeutic activities. Using monoclonal antibody 81C6 as a carrier for I-131 results in the targeted imaging and/or destruction of cells expressing tenascin. Tenascin is an extracellular matrix protein which is overexpressed in gliomas and other cancers.

Display Name: Iodine I 131 Monoclonal Antibody 81C6

Label: Iodine I 131 Monoclonal Antibody 81C6

NCI Thesaurus Code: C2488 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0796329  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
iodine I 131 MOAB 81C6
Iodine I 131 Monoclonal Antibody 81C6
I 131 Monoclonal Antibody 81C6
Neuradiab

External Source Codes: 
PDQ Closed Trial Search ID 43146
PDQ Open Trial Search ID 43146 (check for NCI PDQ open clinical trial info)
UMLS CUI C0796329

Other Properties:
     Name Value (qualifiers indented underneath)
code C2488
Contributing_Source CTRP
Legacy_Concept_Name I_131_Monoclonal_Antibody_81C6
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2488

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