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Version: 17.06d (Release date: 2017-06-26)
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Iodine I 124 Monoclonal Antibody A33 (Code C2440)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Iodine I 124 Monoclonal Antibody A33

Definition: A radioimmunoconjugate of a humanized monoclonal antibody (MoAb) A33 labelled with Iodine 124 (I-124). MoAb A33 recognizes A33 antigen, a 43 KDa transmembrane glycoprotein of the immunoglobulin superfamily, highly and homogenously expressed in 95% of colorectal cancer metastases, with only restricted expression in normal colonic mucosa. I-124 MoAb A33 delivers beta particle emitting I-124 nuclide directly to metastatic colorectal tissues, thereby this agent could be used in kinetics studies or radioimmunotherapy.

Label: Iodine I 124 Monoclonal Antibody A33

NCI Thesaurus Code: C2440 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0677678  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
iodine I 124 MOAB A33
Iodine I 124 Monoclonal Antibody A33
I 124 Monoclonal Antibody A33

External Source Codes: 
PDQ Closed Trial Search ID 42707
PDQ Open Trial Search ID 42707 (check for NCI PDQ open clinical trial info)
UMLS CUI C0677678

Other Properties:
     Name Value (qualifiers indented underneath)
code C2440
Legacy_Concept_Name I_124_Monoclonal_Antibody_A33
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Indicator, Reagent, or Diagnostic Aid

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2440

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