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Version: 17.12d (Release date: 2017-12-26)
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Iodine I 131 Monoclonal Antibody 3F8 (Code C2431)

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Terms & Properties

Preferred Name: Iodine I 131 Monoclonal Antibody 3F8

Definition: A radioimmunoconjugate consisting of 3F8, a murine anti-GD2 ganglioside monoclonal antibody labeled with iodine 131 (I-131), with radioimaging and radioimmunotherapeutic properties. Using monoclonal antibody 3F8 as a carrier for I-131 results in the targeted imaging and/or destruction of cells expressing GD2. GD2 is a ganglioside which is overexpressed in malignant melanoma, neuroblastoma, and small cell carcinoma of the lung. (NCI04)

Label: Iodine I 131 Monoclonal Antibody 3F8

NCI Thesaurus Code: C2431 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0393072  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
I 131 Monoclonal Antibody 3F8
iodine I 131 MOAB 3F8
Iodine I 131 Monoclonal Antibody 3F8

External Source Codes: 
PDQ Closed Trial Search ID 42680
PDQ Open Trial Search ID 42680 (check for NCI PDQ open clinical trial info)
UMLS CUI C0393072

Other Properties:
     Name Value (qualifiers indented underneath)
code C2431
Legacy_Concept_Name I_131_Monoclonal_Antibody_3F8
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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