|Recombinant Adenovirus-p53 SCH-58500 (Code C2423)|
|Terms & Properties|
Preferred Name: Recombinant Adenovirus-p53 SCH-58500
Definition: A genetically-engineered adenovirus that contains the gene that encodes the human tumor-suppressor protein p53 with potential antineoplastic activity. Recombinant adenovirus-p53 SCH-58500 delivers p53 into tumor cells, which may result in p53-mediated cell cycle arrest and apoptosis.
NCI-GLOSS Definition: A substance that has been studied in the treatment of some types of cancer. rAd/p53 is a weakened adenovirus that carries the p53 gene into tumor cells, causing them to die. It is a type of gene therapy.
Label: Recombinant Adenovirus-p53 SCH-58500
NCI Metathesaurus Link: C1514767 (see NCI Metathesaurus info)
Synonyms & Abbreviations: (see Synonym Details)
|Recombinant Adenovirus-p53 SCH-58500|
External Source Codes:
|PDQ Closed Trial Search ID||42631|
|PDQ Open Trial Search ID||42631 (check for NCI PDQ open clinical trial info)|
|Name||Value (qualifiers indented underneath)|
|Accepted_Therapeutic_Use_For||Primary ovarian cancer|
Additional Concept Data:
|Defined Fully by Roles: No|