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Version: 17.06d (Release date: 2017-06-26)
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Carcinoembryonic Antigen Peptide 1 (Code C2414)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Carcinoembryonic Antigen Peptide 1

Definition: A nine amino acid peptide fragment of carcinoembryonic antigen (CEA), a protein that is overexpressed in several cancer cell types, including gastrointestinal, breast, and non-small cell lung. Autologous vaccination with activated autologous dendritic cells (DC) or peripheral blood mononuclear cells (PBMC) which have been exposed to CEA peptide 1 in vitro may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing CEA, thereby inhibiting tumor growth. (NCI04)

NCI-GLOSS Definition: A small piece of a tumor marker called carcinoembryonic antigen (CEA). CEA may be found in the blood of people who have colon cancer, other types of cancer or diseases, or who smoke tobacco. Carcinoembryonic antigen peptide-1 is used to make a vaccine that may help stimulate the body's immune system to kill cancer cells.

Label: Carcinoembryonic Antigen Peptide 1

NCI Thesaurus Code: C2414 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0393002  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
CAP-1
Carcinoembryonic Antigen Peptide-1
carcinoembryonic antigen peptide-1
Carcinoembryonic Antigen Peptide 1
Carcinoembryonic Peptide-1
CEA peptide-1
CEA Peptide 1
CEA Peptide 9-mer

External Source Codes: 
NSC Code 672683 (see NCI DTP info)
PDQ Closed Trial Search ID 42585
PDQ Open Trial Search ID 42585 (check for NCI PDQ open clinical trial info)
UMLS CUI C0393002

Other Properties:
     Name Value (qualifiers indented underneath)
code C2414
Legacy_Concept_Name Carcinoembryonic_Antigen_Peptide_1
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Immunologic Factor
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: Yes  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2414

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