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National Cancer Institute
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Version: 17.06d (Release date: 2017-06-26)
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GM2-KLH Vaccine (Code C2376)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: GM2-KLH Vaccine

Definition: A cancer vaccine consisting of GM2 ganglioside, a melanoma-specific antigen, conjugated with the immunostimulant keyhole limpet hemocyanin. Vaccination with GM2-KLH vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against GM2 ganglioside-expressing melanoma cells, resulting in tumor growth inhibition. (NCI04)

NCI-GLOSS Definition: A substance used to stimulate the production of antibodies that fight certain cancer cells.

Display Name: GM2-KLH Vaccine

Label: GM2-KLH Vaccine

NCI Thesaurus Code: C2376 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0281208  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
GM2-KLH
GM2-KLH Ganglioside
GM2-KLH Vaccine
GM2-KLH vaccine
KLH-conjugated GM2 Ganglioside Vaccine

External Source Codes: 
PDQ Closed Trial Search ID 41589
PDQ Open Trial Search ID 41589 (check for NCI PDQ open clinical trial info)
UMLS CUI C0281208

Other Properties:
     Name Value (qualifiers indented underneath)
code C2376
Contributing_Source CTRP
Legacy_Concept_Name GM2-KLH_Vaccine
Semantic_Type Immunologic Factor
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2376

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