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Version: 17.06d (Release date: 2017-06-26)
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Monoclonal Antibody 14G2A (Code C2368)

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Terms & Properties

Preferred Name: Monoclonal Antibody 14G2A

Definition: A murine monoclonal antibody directed against the ganglioside GD2 with potential antineoplastic activity. Monoclonal antibody 14G2A binds to the ganglioside GD2 and induces antibody-dependent cell mediated cytotoxicity and complement-dependent cytotoxicity against GD2-expressing tumor cells. GD2 is overexpressed in malignant melanoma, neuroblastoma, osteosarcoma, and small cell carcinoma of the lung. (NCI04)

Label: Monoclonal Antibody 14G2A

NCI Thesaurus Code: C2368 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0280838  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
14G2A
14G2A, monoclonal antibody
Antibody 14G2A, Monoclonal
MoAb 14G2A
Monoclonal Antibody 14G2A

External Source Codes: 
NSC Code 624345 (see NCI DTP info)
PDQ Closed Trial Search ID 41244
PDQ Open Trial Search ID 41244 (check for NCI PDQ open clinical trial info)
UMLS CUI C0280838

Other Properties:
     Name Value (qualifiers indented underneath)
code C2368
Legacy_Concept_Name Monoclonal_Antibody_14G2A
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Immunologic Factor

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2368

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