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Version: 17.06d (Release date: 2017-06-26)
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Methylmercaptopurine Riboside (Code C2352)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Methylmercaptopurine Riboside

Definition: A purine derivative with antineoplastic and anti-angiogenic properties. 6-methylmercaptopurine riboside (6-MMPR) inhibits amidophosphoribosyltransferase, the first committed step in de novo purine synthesis, and inhibits fibroblast growth factor-2 (FGF2)-induced cell proliferation. (NCI04)

Label: Methylmercaptopurine Riboside

NCI Thesaurus Code: C2352 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0025828  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
6-(methylmercapto)purine ribonucleoside
6-(methylthio)purine ribonucleoside
6-(methylthio)purine riboside
6-(methylthio) inosine
6-methylmercaptopurine riboside
6-methylthioinosine
6-methyl MP riboside
6-MMPR
9H-Purine, 6-(methylthio)-9-.beta.-D-ribofuranosyl-, dihydrate
9H-Purine, 6-(methylthio)-9-.beta.-D-ribofuranosyl- (8CI 9CI)
9H-purine, 6-(methylthio)-9-beta-D-ribofuranosyl-, dihydrate
9H-purine, 6-(methylthio)-9-beta-D-ribofuranosyl- (8CI 9CI)
9H-purine, 6-(methylthio)-9beta-D-ribofuranosyl
beta-D-ribosyl-6-methylthiopurine
Methylmercaptopurine Riboside
methylthioinosine
MMPR
NCI-C04784
purine-6-thiol,6-methyl-9-ribofuranosyl
SQ 21977

External Source Codes: 
CAS Registry Number 342-69-8 (see NLM ChemIDplus info)
NSC Code 40774 (see NCI DTP info)
PDQ Closed Trial Search ID 39497
PDQ Open Trial Search ID 39497 (check for NCI PDQ open clinical trial info)
UMLS CUI C0025828

Other Properties:
     Name Value (qualifiers indented underneath)
code C2352
Legacy_Concept_Name Methylmercaptopurine_Riboside
Semantic_Type Nucleic Acid, Nucleoside, or Nucleotide
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2352

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