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Version: 17.06d (Release date: 2017-06-26)
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Corticotropin (Code C2282)

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Terms & Properties

Preferred Name: Corticotropin

Definition: Corticotropin (39 aa, ~5 kDa) is encoded by the human POMC gene. This protein plays a role in the stimulation of cortisol secretion by the adrenal gland.

NCI-GLOSS Definition: A hormone made in the pituitary gland. ACTH acts on the outer part of the adrenal gland to control its release of corticosteroid hormones. More ACTH is made during times of stress.

Label: Corticotropin

NCI Thesaurus Code: C2282 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0001655  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
ACTH
adrenocorticotropic hormone
Adrenocorticotropic Hormone
Adrenocorticotropin
Corticotropin
corticotropin

External Source Codes: 
CAS Registry Number 9002-60-2 (see NLM ChemIDplus info)
OMIM Number 176830 (see OMIM info)
ChEBI ID CHEBI:3892 (see ChEBI info)
Swiss Prot P01189 (see UniProt/Swiss-Prot info)
UMLS CUI C0001655

Other Properties:
     Name Value (qualifiers indented underneath)
code C2282
DesignNote Corticotropin is secreted by the anterior portion of the pituitary gland.
Legacy_Concept_Name Adrenocorticotropic_Hormone
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Hormone

Additional Concept Data: 
Defined Fully by Roles: Yes  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2282

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