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Version: 17.08d (Release date: 2017-08-28)
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Gonadotrophin Releasing Hormone (Code C2270)

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Terms & Properties

Preferred Name: Gonadotrophin Releasing Hormone

Definition: Specifically expressed in hypothalamic neurons as a preproprotein, Gonadotropin Releasing Hormones (GnRH Family) are secreted into the median eminence capillary plexus, bind to receptors on anterior pituitary gonadotrophs, and stimulate the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) to control female reproduction.

NCI-GLOSS Definition: A hormone made by the hypothalamus (part of the brain). GnRH causes the pituitary gland to make luteinizing hormone (LH) and follicle-stimulating hormone (FSH). These hormones are involved in reproduction.

Label: Gonadotrophin Releasing Hormone

NCI Thesaurus Code: C2270 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0023610  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
AY-24031
D-His-6-Pro-8-NEt-LHRH
Follicle Stimulating Hormone-Releasing Factor
GN-RH
GnRH
Gonadoliberin
Gonadorelin
Gonadorelinum
Gonadotrophin Releasing Hormone
gonadotropin-releasing hormone
Hoe- 471
LH-RF
LH-RH
LH/FSH-RF
LH/FSH-RH
LHRH
Luliberin
Luteinising Hormone-Releasing Factor
Luteinizing Hormone-Releasing Factor
luteinizing hormone-releasing hormone
Luteinizing Hormone-Releasing Hormone

External Source Codes: 
CAS Registry Number 33515-09-2 (see NLM ChemIDplus info)
UMLS CUI C0023610

Other Properties:
     Name Value (qualifiers indented underneath)
code C2270
Legacy_Concept_Name Gonadotrophin_Releasing_Hormone
Semantic_Type Hormone

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2270

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