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Version: 17.06d (Release date: 2017-06-26)
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Monoclonal Antibody 4B5 Anti-Idiotype Vaccine (Code C2227)

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Terms & Properties

Preferred Name: Monoclonal Antibody 4B5 Anti-Idiotype Vaccine

Definition: A humanized anti-idiotypic (anti-Id) monoclonal antibody (MoAb) that mimics the disialoganglioside GD2 with potential immunostimulating and antineoplastic activities. Upon administration, monoclonal antibody 4B5 anti-idiotype vaccine may elicit both cellular and humoral immune responses against GD2- expressing tumor cells. GD2 is a glycosphingolipid (ceramide and oligosaccharide) that may be highly expressed by melanomas and other neuroectodermal tumors, while only minimally expressed by normal tissues.

Label: Monoclonal Antibody 4B5 Anti-Idiotype Vaccine

NCI Thesaurus Code: C2227 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0879386  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
4B5 monoclonal antibody anti-idiotype vaccine
MoAb 4B5 anti-idiotype vaccine
Monoclonal Antibody 4B5 Anti-Idiotype Vaccine

External Source Codes: 
PDQ Closed Trial Search ID 37797
PDQ Open Trial Search ID 37797 (check for NCI PDQ open clinical trial info)
UMLS CUI C0879386

Other Properties:
     Name Value (qualifiers indented underneath)
code C2227
Legacy_Concept_Name Monoclonal_Antibody_4B5_Anti-Idiotype_Vaccine
Semantic_Type Immunologic Factor
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2227

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