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National Cancer Institute
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Version: 17.06d (Release date: 2017-06-26)
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Bispecific Antibody MDX447 (Code C2207)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Bispecific Antibody MDX447

Definition: An antibody with potential antineoplastic activity. Specific for both the high-affinity immunoglobulin G (IgG) receptor CD64 and epidermal growth factor receptor (EGFR), bispecific antibody MDX447 may enhance cellular immune responses against EGFR positive cells, resulting in increased tumor cell lysis. (NCI04)

Label: Bispecific Antibody MDX447

NCI Thesaurus Code: C2207 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0879492  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Bispecific Antibody MDX447
BsAb MDX447
EMD 82633
MDX-447

External Source Codes: 
PDQ Closed Trial Search ID 37952
PDQ Open Trial Search ID 37952 (check for NCI PDQ open clinical trial info)
UMLS CUI C0879492

Other Properties:
     Name Value (qualifiers indented underneath)
code C2207
Legacy_Concept_Name Bispecific_Antibody_MDX447
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2207

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