|Acridine Carboxamide (Code C2203)|
|Terms & Properties|
Preferred Name: Acridine Carboxamide
Definition: A tricyclic acridine-based (or carboxamide-based) drug with dual topoisomerase inhibitor and potential antineoplastic activities. Acridine carboxamide inhibits both topoisomerases I and II and intercalates into DNA, resulting in DNA damage, the disruption of DNA repair and replication, the inhibition of RNA and protein synthesis, and cell death.
NCI-GLOSS Definition: A substance being studied in the treatment of cancer. It is a type of topoisomerase inhibitor.
Label: Acridine Carboxamide
NCI Metathesaurus Link: C0919282 (see NCI Metathesaurus info)
Synonyms & Abbreviations: (see Synonym Details)
External Source Codes:
|FDA UNII Code||0N3V8R4E13|
|PDQ Closed Trial Search ID||37776|
|PDQ Open Trial Search ID||37776 (check for NCI PDQ open clinical trial info)|
|Name||Value (qualifiers indented underneath)|
Additional Concept Data:
|Defined Fully by Roles: No|