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Version: 17.12d (Release date: 2017-12-26)
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Alfentanil Hydrochloride (Code C220)

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Terms & Properties

Preferred Name: Alfentanil Hydrochloride

Definition: The hydrochloride salt of alfentanil, a synthetic short-acting opioid with analgesic and local anesthesia enhancing activity. Alfentanil primarily binds to mu-opioid receptor, a G-protein-coupled receptor, thereby mimicking the actions of morphine, the prototypical mu receptor agonist. This agent induces anti-nociception responses mediated through inhibiting the release of various neurotransmitters such as substance P, GABA, dopamine, acetylcholine and noradrenaline; in addition, the release of vasopressin, somatostatin, insulin and glucagon are also inhibited.

Label: Alfentanil Hydrochloride

NCI Thesaurus Code: C220 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0002025  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Alfentanil Hydrochloride

External Source Codes: 
CAS Registry Number 70879-28-6 (see NLM ChemIDplus info)
PDQ Closed Trial Search ID 42783
PDQ Open Trial Search ID 42783 (check for NCI PDQ open clinical trial info)
UMLS CUI C0002025

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C21H32N6O3.ClH.H2O
code C220
Contributing_Source FDA
Legacy_Concept_Name Alfentanil_Hydrochloride
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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