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Version: 17.06d (Release date: 2017-06-26)
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Emepepimut-S (Code C2195)

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Terms & Properties

Preferred Name: Emepepimut-S

Definition: A liposome-encapsulated peptide vaccine consisting of a synthetic peptide derived from the mucin 1 (MUC-1) antigen with potential antineoplastic activity. Upon vaccination, MUC-1 peptide vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against MUC-1-expressing tumor cells, resulting in growth inhibition. MUC-1 antigen is a high-molecular-weight transmembrane glycoprotein that is overexpressed on the cell surfaces of many epithelial tumor cells as well as on the cell surfaces of some B-cell lymphoma cells and multiple myeloma cells.

Display Name: Emepepimut-S

Label: Emepepimut-S

NCI Thesaurus Code: C2195 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1832016  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
BLP25 Liposome Vaccine
EMD 531444
Glycine, L-seryl-L-threonyl-L-alanyl-L-prolyl-L-prolyl-L-alanyl-L-histidylglycyl-L-valyl-L-threonyl-L-seryl-L-alanyl-L-prolyl-L-alpha-aspartyl-L-threonyl-L-arginyl-L-prolyl-L-alanyl-L-prolylglycyl-L-seryl-L-threonyl-L-alanyl-L-prolyl-L-prolyl-N6-(1-oxohexadecyl)-L-lysyl-

External Source Codes: 
PDQ Closed Trial Search ID 529341
PDQ Open Trial Search ID 529341 (check for NCI PDQ open clinical trial info)
UMLS CUI C1832016

Other Properties:
     Name Value (qualifiers indented underneath)
code C2195
Contributing_Source CTRP
Legacy_Concept_Name BLP25
Semantic_Type Immunologic Factor
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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