|Lopinavir (Code C2095)|
|Terms & Properties|
Preferred Name: Lopinavir
Definition: A peptidomimetic HIV protease inhibitor that retains activity against HIV protease with the Val 82 mutation. Lopinavir is less affected by binding to serum proteins than the structurally-related drug ritonavir.
NCI-GLOSS Definition: A drug used with another drug, called ritonavir, to treat infection with HIV (the virus that causes AIDS). It is also being studied in the treatment of some types of cancer. Lopinavir blocks the ability of HIV to make copies of itself and may help some anticancer drugs work better. It is a type of anti-HIV agent and a type of protease inhibitor.
Display Name: Lopinavir
NCI Metathesaurus Link: C0674432 (see NCI Metathesaurus info)
Synonyms & Abbreviations: (see Synonym Details)
External Source Codes:
|CAS Registry Number||192725-17-0 (see NLM ChemIDplus info)|
|FDA UNII Code||2494G1JF75|
|PDQ Closed Trial Search ID||540623|
|PDQ Open Trial Search ID||540623 (check for NCI PDQ open clinical trial info)|
|Name||Value (qualifiers indented underneath)|
Additional Concept Data:
|Defined Fully by Roles: No|